HK3

Across TCGA patient cohorts, HK3 protein abundance is significantly associated with the RNA expression of many other genes, with 21,013 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HK3-associated genes across cancer lineages are SIRPB1, TLR8, and MEFV. Each is linked with HK3 in more than 9 cancer types. Because this analysis shows association rather than direction, both HK3-to-partner and partner-to-HK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK3 versus SIRPB1 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HK3→partner) and Y-score (partner→HK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIRPB1 →	+0.684	+0.693	<.001	<.001	3	10
GBM	TLR8 →	+0.994	+0.913	<.001	<.001	3	10
LSCC	MEFV →	+0.890	+0.542	<.001	<.001	3	10
BRCA	IL4I1 →	+1.494	+0.824	<.001	<.001	3	10
UCEC	LILRB1 →	+0.859	+0.662	<.001	<.001	3	10
GBM	ADGRE2 →	+0.998	+0.954	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,013 associations by consensus.

HK3 vs SIRPB1 — UCEC

Explore this scatter interactively →