HK1

Across TCGA patient cohorts, HK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,999 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HK1-associated proteins across cancer lineages are VPS26A, FRMD6_S544, and G6PD. Each is linked with HK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HK1-to-partner and partner-to-HK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK1 versus VPS26A in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HK1→partner) and Y-score (partner→HK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VPS26A →	+0.191	+0.386	<.001	<.001	3	5
LSCC	FRMD6_S544 →	+0.878	+0.672	<.001	<.001	3	4
LSCC	G6PD →	+0.645	+0.671	<.001	<.001	3	4
HNSC	KIFBP →	+0.206	+0.427	<.001	.005	2	5
UCEC	RERE_S656 →	-0.358	-0.691	.001	.001	3	4
GBM	S100A11 →	+0.673	+0.351	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,999 associations by consensus.

HK1 vs VPS26A — GBM

Explore this scatter interactively →