HK1

Across TCGA patient cohorts, HK1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HK1-associated genes across cancer lineages are MYOF, BAG3, and INPP5F. Each is linked with HK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HK1-to-partner and partner-to-HK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HK1 versus MYOF in COAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HK1→partner) and Y-score (partner→HK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MYOF →	+1.056	+0.269	<.001	<.001	3	5
BRCA	BAG3 →	+0.696	+0.287	.001	.001	3	4
GBM	INPP5F →	+0.540	+0.463	<.001	<.001	3	4
COAD	KIFBP →	+0.468	+0.234	<.001	.002	3	4
LSCC	CD109 →	+1.189	+0.263	<.001	.008	3	4
CCRCC	PKHD1 →	-1.862	-0.262	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,919 associations by consensus.

HK1 vs MYOF — COAD

Explore this scatter interactively →