HK1

Across TCGA cell cohorts, HK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,694 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HK1-associated GO terms across cancer lineages are Glycolytic process through fructose-6-phosphate, Glycolytic process through glucose-6-phosphate, and Glucose catabolic process. Each is linked with HK1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HK1-to-partner and partner-to-HK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycolytic process through fructose-6-phosphate grouped by HK1-low versus HK1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HK1→partner) and Y-score (partner→HK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Glycolytic process through fructose-6-phosphate →	+0.162	+1.661	<.001	<.001	3	16
STOMACH	Glycolytic process through glucose-6-phosphate →	+0.162	+1.661	<.001	<.001	3	16
STOMACH	Glucose catabolic process →	+0.154	+1.514	<.001	<.001	3	14
STOMACH	Pyruvate metabolic process →	+0.120	+2.122	<.001	<.001	3	14
STOMACH	Canonical glycolysis →	+0.172	+1.778	<.001	<.001	3	14
STOMACH	Glucose catabolic process to pyruvate →	+0.172	+1.778	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,694 associations by consensus.

Glycolytic process through fructose-6-phosphate by HK1 expression — STOMACH

Explore this box plot interactively →