HIP1

Across TCGA patient cohorts, HIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,655 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HIP1-associated genes across cancer lineages are SEMA5A, DLC1, and CNPY4. Each is linked with HIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HIP1-to-partner and partner-to-HIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIP1 versus SEMA5A in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIP1→partner) and Y-score (partner→HIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEMA5A →	+1.029	+0.323	.001	<.001	3	7
CCRCC	DLC1 →	+0.820	+0.285	<.001	<.001	3	7
UCEC	CNPY4 →	+0.827	+0.393	<.001	<.001	3	7
CCRCC	PRKG1 →	+0.938	+0.307	<.001	<.001	3	7
BRCA	MAGI2-AS3 →	+0.665	+0.334	.001	<.001	3	7
UCEC	DKK3 →	+0.993	+0.385	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,655 associations by consensus.

HIP1 vs SEMA5A — BRCA

Explore this scatter interactively →