HIP1

Across TCGA cell cohorts, HIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,856 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HIP1-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, DNA-templated transcription initiation, and RNA export from nucleus. Each is linked with HIP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both HIP1-to-partner and partner-to-HIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by HIP1-low versus HIP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIP1→partner) and Y-score (partner→HIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of gene expression, epigenetic →	+0.084	+2.077	<.001	.004	3	14
STOMACH	DNA-templated transcription initiation →	+0.051	+1.947	.004	<.001	3	13
STOMACH	RNA export from nucleus →	+0.109	+2.066	.001	.002	3	13
STOMACH	Regulation of nucleotide-excision repair →	+0.134	+1.859	.001	.002	3	13
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.070	+1.424	.002	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule polymerization or depolymerization →	+0.063	+0.966	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,856 associations by consensus.

Negative regulation of gene expression, epigenetic by HIP1 expression — STOMACH

Explore this box plot interactively →