HINFP

Across TCGA cell cohorts, HINFP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,049 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HINFP-associated GO terms across cancer lineages are Regulation of mRNA processing, Pre-mRNA catabolic process, and Regulation of organelle assembly. Each is linked with HINFP in more than 15 cancer types. Because this analysis shows association rather than direction, both HINFP-to-partner and partner-to-HINFP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by HINFP-low versus HINFP-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HINFP→partner) and Y-score (partner→HINFP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of mRNA processing →	+0.112	+0.747	<.001	<.001	3	16
BONE	Pre-mRNA catabolic process →	+0.249	+0.954	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.050	+0.918	<.001	.005	3	16
BONE	Establishment of RNA localization →	+0.105	+0.915	<.001	<.001	3	15
SOFT_TISSUE	RNA localization →	+0.100	+0.904	<.001	<.001	3	15
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.210	+0.999	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,049 associations by consensus.

Regulation of mRNA processing by HINFP expression — STOMACH

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