Across TCGA patient cohorts, HIKESHIP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,144 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HIKESHIP1-associated proteins across cancer lineages are CNP_S9, GPX4, and REXO4. Each is linked with HIKESHIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HIKESHIP1-to-partner and partner-to-HIKESHIP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIKESHIP1→partner) and Y-score (partner→HIKESHIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNP_S9 →	-1.162	-0.749	.001	<.001	3	3
BRCA	GPX4 →	-0.346	-0.911	<.001	<.001	3	3
BRCA	REXO4 →	+0.470	+0.917	<.001	<.001	3	3
GBM	SNRPA1 →	+0.240	+0.699	.005	.004	3	3
UCEC	FRMD6_S544 →	+0.652	+1.108	.003	<.001	3	3
GBM	ARFGEF3 →	-0.473	-0.710	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,144 associations by consensus.

Exploration

HIKESHIP1 survival (RNA) · tumor vs normal (RNA) · all HIKESHIP1 data types