HIGD2A

Across TCGA patient cohorts, HIGD2A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HIGD2A-associated genes across cancer lineages are Chondrocytes and Fibroblasts. Each is linked with HIGD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both HIGD2A-to-partner and partner-to-HIGD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocytes grouped by HIGD2A-low versus HIGD2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD2A→partner) and Y-score (partner→HIGD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Chondrocytes →	+0.011	+3.286	.006	.012	3	1
UCEC	Fibroblasts →	+0.042	+3.393	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Chondrocytes by HIGD2A expression — UCEC

Explore this box plot interactively →