HIGD1B

Across TCGA patient cohorts, HIGD1B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,673 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HIGD1B-associated proteins across cancer lineages are PRKG1, ERG_S81, and SORBS3. Each is linked with HIGD1B in more than 8 cancer types. Because this analysis shows association rather than direction, both HIGD1B-to-partner and partner-to-HIGD1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIGD1B versus PRKG1 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1B→partner) and Y-score (partner→HIGD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.873	+0.735	<.001	<.001	3	9
CCRCC	ERG_S81 →	+0.691	+0.702	<.001	<.001	3	8
OV	SORBS3 →	+0.517	+0.694	.001	<.001	3	7
CCRCC	SHROOM4_S299 →	+0.650	+1.065	<.001	<.001	3	7
CCRCC	MMRN2 →	+0.628	+1.076	<.001	<.001	3	7
BRCA	NID1 →	+0.536	+0.749	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,673 associations by consensus.

HIGD1B vs PRKG1 — UCEC

Explore this scatter interactively →