HIGD1AP9

Across TCGA patient cohorts, HIGD1AP9 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,639 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP9-associated GO terms across cancer lineages are RNA-templated DNA biosynthetic process, Regulation of DNA biosynthetic process, and RNA localization. Each is linked with HIGD1AP9 in more than 21 cancer types. Because this analysis shows association rather than direction, both HIGD1AP9-to-partner and partner-to-HIGD1AP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA-templated DNA biosynthetic process grouped by HIGD1AP9-low versus HIGD1AP9-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP9→partner) and Y-score (partner→HIGD1AP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA-templated DNA biosynthetic process →	+0.071	+0.371	<.001	<.001	3	22
STAD	Regulation of DNA biosynthetic process →	+0.050	+0.293	<.001	<.001	3	20
STAD	RNA localization →	+0.061	+0.319	<.001	<.001	3	20
STAD	mRNA export from nucleus →	+0.062	+0.361	<.001	<.001	3	20
STAD	Peptidyl-lysine modification →	+0.053	+0.361	<.001	<.001	3	20
ESCA	Regulation of post-translational protein modification →	+0.059	+0.277	.002	<.001	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,639 associations by consensus.

RNA-templated DNA biosynthetic process by HIGD1AP9 expression — ESCA

Explore this box plot interactively →