HIGD1AP18

Across TCGA patient cohorts, HIGD1AP18 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,933 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HIGD1AP18-associated proteins across cancer lineages are PPIB, RBM12B, and RBMX_S88. Each is linked with HIGD1AP18 in more than 3 cancer types. Because this analysis shows association rather than direction, both HIGD1AP18-to-partner and partner-to-HIGD1AP18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HIGD1AP18 versus PPIB in LSCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP18→partner) and Y-score (partner→HIGD1AP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPIB →	-0.385	-0.648	<.001	.002	3	4
GBM	RBM12B →	+0.180	+0.432	.001	<.001	3	4
HNSC	RBMX_S88 →	+0.351	+0.727	.001	.003	3	4
LUAD	RPL26 →	-0.440	-0.461	.003	.002	3	3
HNSC	RPRD2 →	+0.275	+0.836	<.001	<.001	3	3
LSCC	RPS6_S240 →	-0.689	-0.598	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,933 associations by consensus.

HIGD1AP18 vs PPIB — LSCC

Explore this scatter interactively →