HIGD1AP17

Across TCGA patient cohorts, HIGD1AP17 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,496 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HIGD1AP17-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Obsolete histone modification, and Epigenetic regulation of gene expression. Each is linked with HIGD1AP17 in more than 20 cancer types. Because this analysis shows association rather than direction, both HIGD1AP17-to-partner and partner-to-HIGD1AP17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of post-translational protein modification grouped by HIGD1AP17-low versus HIGD1AP17-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIGD1AP17→partner) and Y-score (partner→HIGD1AP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of post-translational protein modification →	+0.053	+0.434	<.001	<.001	3	21
ESCA	Obsolete histone modification →	+0.054	+0.418	<.001	<.001	3	20
ESCA	Epigenetic regulation of gene expression →	+0.057	+0.488	<.001	<.001	3	20
ESCA	Base-excision repair →	+0.047	+0.356	<.001	<.001	3	20
ESCA	Regulation of post-translational protein modification →	+0.055	+0.441	<.001	<.001	3	20
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.054	+0.392	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,496 associations by consensus.

Positive regulation of post-translational protein modification by HIGD1AP17 expression — ESCA

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