HID1

Across TCGA pan-cancer cohorts, HID1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated HID1 data layer compared with 20 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher HID1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HID1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and GBM are the cancer types where HID1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.510	0.305	<.001	43	view →
UCEC	DFS	Quartile	II,III,IV	1.000	0.464	.018	20	view →
GBM	DFS	Tertile	All	0.847	0.645	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

HID1–PDAC (DFS)

Open the PDAC breakdown →