HID1

Across TCGA cell cohorts, HID1 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HID1-associated genes across cancer lineages are BMP15, OR2T5, and C1orf141. Each is linked with HID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HID1-to-partner and partner-to-HID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMP15 grouped by HID1-low versus HID1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HID1→partner) and Y-score (partner→HID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	BMP15 →	+0.012	+4.781	<.001	.003	3	1
BREAST	OR2T5 →	+0.025	+4.781	<.001	.003	3	1
BREAST	C1orf141 →	+0.037	+4.781	<.001	.003	3	1
BLOOD_Leukemia	PHOX2B →	+0.016	+3.365	<.001	.005	3	1
BLOOD_Leukemia	FAM71F1 →	+0.148	+3.736	.001	.008	3	1
BLOOD_Leukemia	NPFFR1 →	+0.014	+3.622	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

BMP15 by HID1 expression — BREAST

Explore this box plot interactively →