HIBADH

Across TCGA cell cohorts, HIBADH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,770 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HIBADH-associated GO terms across cancer lineages are Endoplasmic reticulum-plasma membrane tethering, Meiotic mismatch repair, and Monocarboxylic acid catabolic process. Each is linked with HIBADH in more than 9 cancer types. Because this analysis shows association rather than direction, both HIBADH-to-partner and partner-to-HIBADH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum-plasma membrane tethering grouped by HIBADH-low versus HIBADH-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HIBADH→partner) and Y-score (partner→HIBADH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endoplasmic reticulum-plasma membrane tethering →	+0.186	+1.216	<.001	<.001	3	10
LARGE_INTESTINE	Meiotic mismatch repair →	+0.105	+0.757	<.001	<.001	3	10
CNS	Monocarboxylic acid catabolic process →	+0.056	+0.872	<.001	<.001	3	8
SKIN	Positive regulation of isotype switching to IgG isotypes →	+0.119	+0.848	<.001	<.001	3	8
CNS	Lipid oxidation →	+0.077	+0.715	<.001	.001	3	8
CNS	Fatty acid catabolic process →	+0.055	+0.769	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,770 associations by consensus.

Endoplasmic reticulum-plasma membrane tethering by HIBADH expression — BONE

Explore this box plot interactively →