HHIPL2

Across TCGA patient cohorts, HHIPL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,099 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HHIPL2-associated GO terms across cancer lineages are Recombinational repair, Telomere maintenance, and Microtubule polymerization or depolymerization. Each is linked with HHIPL2 in more than 18 cancer types. Because this analysis shows association rather than direction, both HHIPL2-to-partner and partner-to-HHIPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Recombinational repair grouped by HHIPL2-low versus HHIPL2-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HHIPL2→partner) and Y-score (partner→HHIPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Recombinational repair →	+0.070	+0.557	<.001	<.001	3	19
SCLC	Telomere maintenance →	+0.082	+0.696	<.001	<.001	3	18
STAD	Microtubule polymerization or depolymerization →	+0.064	+0.275	<.001	<.001	3	18
SCLC	Telomere organization →	+0.073	+0.714	<.001	<.001	3	18
SCLC	Regulation of telomere maintenance →	+0.100	+0.671	<.001	<.001	3	18
SCLC	Regulation of chromosome organization →	+0.090	+0.444	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,099 associations by consensus.

Recombinational repair by HHIPL2 expression — SCLC

Explore this box plot interactively →