HHIPL2

Across TCGA cell cohorts, HHIPL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,730 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HHIPL2-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Nuclear transport, and Lipoprotein transport. Each is linked with HHIPL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HHIPL2-to-partner and partner-to-HHIPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by HHIPL2-low versus HHIPL2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HHIPL2→partner) and Y-score (partner→HHIPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Calcium-independent cell-matrix adhesion →	+0.214	+0.830	<.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.060	+0.923	.003	.002	3	9
STOMACH	Lipoprotein transport →	+0.114	+0.872	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.059	+0.819	.003	.009	3	8
LARGE_INTESTINE	Cell division →	+0.049	+0.391	<.001	.008	3	8
LARGE_INTESTINE	RNA export from nucleus →	+0.057	+0.457	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,730 associations by consensus.

Calcium-independent cell-matrix adhesion by HHIPL2 expression — STOMACH

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