HHIPL1

Across TCGA patient cohorts, HHIPL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,867 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HHIPL1-associated proteins across cancer lineages are TIMP2, ISLR, and PALLD. Each is linked with HHIPL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HHIPL1-to-partner and partner-to-HHIPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HHIPL1 versus TIMP2 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HHIPL1→partner) and Y-score (partner→HHIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TIMP2 →	+0.792	+0.656	<.001	<.001	3	9
BRCA	ISLR →	+0.986	+0.775	<.001	<.001	3	9
CCRCC	PALLD →	+0.746	+0.430	<.001	<.001	3	9
HNSC	PDLIM3 →	+1.182	+0.487	<.001	<.001	3	9
BRCA	PDLIM4 →	+0.866	+0.738	<.001	<.001	3	9
CCRCC	THBS2 →	+1.420	+0.464	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,867 associations by consensus.

HHIPL1 vs TIMP2 — BRCA

Explore this scatter interactively →