HHIPL1

Across TCGA patient cohorts, HHIPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,158 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HHIPL1-associated genes across cancer lineages are COMP, SLC1A4, and PRND. Each is linked with HHIPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HHIPL1-to-partner and partner-to-HHIPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HHIPL1 versus COMP in PDAC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HHIPL1→partner) and Y-score (partner→HHIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	COMP →	+1.854	+0.631	.009	.004	3	2
GBM	SLC1A4 →	-0.630	-0.631	.002	<.001	3	2
BRCA	PRND →	+1.092	+0.509	<.001	<.001	3	2
PDAC	CYS1 →	+1.467	+0.907	.002	<.001	3	2
BRCA	EMILIN1 →	+1.549	+0.582	<.001	<.001	3	2
BRCA	ADAMTS14 →	+1.451	+0.524	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,158 associations by consensus.

HHIPL1 vs COMP — PDAC

Explore this scatter interactively →