HHEX

Across TCGA patient cohorts, HHEX RNA expression is significantly associated with the protein abundance of many other proteins, with 20,037 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HHEX-associated proteins across cancer lineages are EVL, FNBP1, and STAB1. Each is linked with HHEX in more than 7 cancer types. Because this analysis shows association rather than direction, both HHEX-to-partner and partner-to-HHEX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HHEX versus EVL in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HHEX→partner) and Y-score (partner→HHEX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EVL →	+0.777	+0.744	<.001	<.001	3	8
OV	FNBP1 →	+0.411	+1.086	.001	<.001	3	8
GBM	STAB1 →	+0.623	+0.641	<.001	<.001	3	7
HNSC	PLEKHO2 →	+0.380	+0.694	<.001	<.001	3	7
BRCA	PREX1 →	+0.763	+0.983	<.001	<.001	3	7
UCEC	SASH3 →	+0.654	+0.730	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,037 associations by consensus.

HHEX vs EVL — UCEC

Explore this scatter interactively →