HHATL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HHATL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,941 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HHATL-associated proteins across cancer lineages are NUP50, PLCB1, and SMC2. Each is linked with HHATL in more than 3 cancer types. Because this analysis shows association rather than direction, both HHATL-to-partner and partner-to-HHATL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HHATL versus NUP50 in GBM, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HHATL→partner) and Y-score (partner→HHATL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNUP50 →-0.282-1.066.003.00834
GBMPLCB1 →+0.652+1.418<.001<.00134
GBMSMC2 →-0.518-1.121.001<.00134
GBMANK2 →+0.461+1.380<.001<.00134
UCECMAP1A_S2106 →+0.586+0.501<.001<.00134
UCECCIBAR2 →+0.624+0.488<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,941 associations by consensus.

HHATL vs NUP50 — GBM

Per-sample scatter of HHATL vs NUP50 in GBM (Pearson r = -0.32).

Explore this scatter interactively →

Exploration