HHATL

Across TCGA patient cohorts, HHATL protein abundance is significantly associated with the RNA expression of many other genes, with 2,494 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HHATL-associated genes across cancer lineages are TMC5, NPY, and CHRNA1. Each is linked with HHATL in more than 1 cancer types. Because this analysis shows association rather than direction, both HHATL-to-partner and partner-to-HHATL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HHATL versus TMC5 in HNSC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HHATL→partner) and Y-score (partner→HHATL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMC5 →	-1.764	-1.174	<.001	<.001	3	2
GBM	NPY →	+0.991	+0.647	.008	<.001	3	2
HNSC	CHRNA1 →	+1.179	+1.230	<.001	<.001	3	2
OV	CFTR →	-4.082	-1.382	<.001	.003	3	2
GBM	SLC22A25 →	+0.458	+0.738	<.001	.001	3	2
GBM	LINC00632 →	+0.910	+0.531	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,494 associations by consensus.

HHATL vs TMC5 — HNSC

Explore this scatter interactively →