HGSNAT

Across TCGA patient cohorts, HGSNAT RNA expression is significantly associated with the protein abundance of many other proteins, with 8,351 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HGSNAT-associated proteins across cancer lineages are POLB, FNTA, and VDAC3. Each is linked with HGSNAT in more than 4 cancer types. Because this analysis shows association rather than direction, both HGSNAT-to-partner and partner-to-HGSNAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGSNAT versus POLB in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HGSNAT→partner) and Y-score (partner→HGSNAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	POLB →	+0.526	+0.375	<.001	<.001	3	5
OV	FNTA →	+0.243	+0.585	.001	.005	3	5
HNSC	VDAC3 →	+0.559	+0.476	<.001	<.001	3	4
UCEC	POMK →	+0.427	+0.399	.001	.002	3	4
GBM	CYB5R1 →	+0.441	+0.251	<.001	<.001	3	4
LSCC	HOOK3 →	+0.260	+0.668	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,351 associations by consensus.

HGSNAT vs POLB — PDAC

Explore this scatter interactively →