HGSNAT

Across TCGA patient cohorts, HGSNAT protein abundance is significantly associated with the RNA expression of many other genes, with 3,688 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HGSNAT-associated genes across cancer lineages are RECQL, SLC17A7, and DSE. Each is linked with HGSNAT in more than 2 cancer types. Because this analysis shows association rather than direction, both HGSNAT-to-partner and partner-to-HGSNAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGSNAT versus RECQL in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HGSNAT→partner) and Y-score (partner→HGSNAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RECQL →	-0.631	-0.505	.005	.008	3	2
GBM	SLC17A7 →	-1.225	-0.290	.005	.003	3	2
OV	DSE →	+0.660	+0.425	.003	<.001	3	2
PDAC	WIPF1 →	+0.532	+0.664	.001	<.001	3	2
LSCC	DAGLA →	-0.511	-0.254	.004	.001	3	2
OV	TM6SF1 →	+0.632	+0.402	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,688 associations by consensus.

HGSNAT vs RECQL — UCEC

Explore this scatter interactively →