HGFAC

Across TCGA patient cohorts, HGFAC RNA expression is significantly associated with the protein abundance of many other proteins, with 8,559 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HGFAC-associated proteins across cancer lineages are STMN1, N4BP1_S300, and NASP_S480. Each is linked with HGFAC in more than 3 cancer types. Because this analysis shows association rather than direction, both HGFAC-to-partner and partner-to-HGFAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGFAC versus STMN1 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HGFAC→partner) and Y-score (partner→HGFAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	STMN1 →	+0.625	+0.635	<.001	.003	3	4
LSCC	N4BP1_S300 →	-0.363	-0.493	.006	<.001	3	3
LUAD	NASP_S480 →	+0.757	+0.477	<.001	<.001	3	3
GBM	TRIOBP →	-0.320	-1.078	<.001	<.001	3	3
LSCC	PPP6R2 →	-0.154	-0.446	.007	.002	3	3
GBM	CAST_S577 →	-0.816	-0.801	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,559 associations by consensus.

HGFAC vs STMN1 — OV

Explore this scatter interactively →