HGFAC

Across TCGA patient cohorts, HGFAC protein abundance is significantly associated with the RNA expression of many other genes, with 15,751 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HGFAC-associated genes across cancer lineages are LYVE1, IL6, and DIPK2B. Each is linked with HGFAC in more than 6 cancer types. Because this analysis shows association rather than direction, both HGFAC-to-partner and partner-to-HGFAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGFAC versus LYVE1 in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HGFAC→partner) and Y-score (partner→HGFAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LYVE1 →	+1.057	+0.310	.002	.006	2	7
GBM	IL6 →	+1.796	+0.569	<.001	<.001	3	6
CCRCC	DIPK2B →	+0.622	+0.349	<.001	<.001	3	6
UCEC	SHE →	+0.703	+0.324	<.001	.007	3	6
UCEC	RHOJ →	+0.854	+0.316	.002	.006	3	5
OV	HSPA12B →	+0.944	+0.316	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,751 associations by consensus.

HGFAC vs LYVE1 — GBM

Explore this scatter interactively →