HGF

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HGF RNA expression is significantly associated with the protein abundance of many other proteins, with 21,172 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HGF-associated proteins across cancer lineages are MYLK, PRKG1, and LMOD1. Each is linked with HGF in more than 8 cancer types. Because this analysis shows association rather than direction, both HGF-to-partner and partner-to-HGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGF versus MYLK in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HGF→partner) and Y-score (partner→HGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYLK →+0.985+1.417<.001<.00139
OVPRKG1 →+0.698+0.768<.001<.00139
UCECLMOD1 →+0.983+0.734<.001<.00139
OVZCCHC24 →+1.169+1.112<.001<.00138
CCRCCSSC5D →+1.027+1.045<.001<.00138
HNSCSTAB1 →+0.627+0.914<.001<.00129
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,172 associations by consensus.

HGF vs MYLK — GBM

Per-sample scatter of HGF vs MYLK in GBM (Pearson r = 0.46).

Explore this scatter interactively →

Exploration