HGD

Across TCGA cell cohorts, HGD RNA expression is significantly associated with the RNA expression of many other genes, with 7,878 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HGD-associated genes across cancer lineages are BAIAP2L2, SGK2, and FRK. Each is linked with HGD in more than 7 cancer types. Because this analysis shows association rather than direction, both HGD-to-partner and partner-to-HGD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HGD versus BAIAP2L2 in STOMACH, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HGD→partner) and Y-score (partner→HGD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	BAIAP2L2 →	+3.311	+3.029	<.001	<.001	3	8
STOMACH	SGK2 →	+3.972	+3.886	<.001	<.001	3	8
LIVER	FRK →	+2.109	+5.038	<.001	<.001	3	8
LIVER	KIF12 →	+2.493	+2.978	<.001	.003	3	8
LIVER	FGFR4 →	+3.371	+3.321	<.001	<.001	3	8
STOMACH	METTL7B →	+2.598	+2.657	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,878 associations by consensus.

HGD vs BAIAP2L2 — STOMACH

Explore this scatter interactively →