HFM1

Across TCGA cell cohorts, HFM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,449 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HFM1-associated GO terms across cancer lineages are Positive regulation of monoatomic ion transport, DNA-templated transcription initiation, and Regulation of microtubule-based process. Each is linked with HFM1 in more than 11 cancer types. Because this analysis shows association rather than direction, both HFM1-to-partner and partner-to-HFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monoatomic ion transport grouped by HFM1-low versus HFM1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HFM1→partner) and Y-score (partner→HFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of monoatomic ion transport →	-0.099	-0.492	.003	.003	3	12
SOFT_TISSUE	DNA-templated transcription initiation →	+0.057	+0.989	.002	<.001	3	12
LUNG_SCLC	Regulation of microtubule-based process →	+0.058	+1.157	.001	<.001	3	11
PANCREAS	Microtubule cytoskeleton organization involved in mitosis →	+0.053	+0.196	<.001	<.001	3	11
BLOOD_Leukemia	Regulation of chromosome organization →	+0.053	+0.588	<.001	<.001	3	11
STOMACH	Positive regulation of mitotic cell cycle →	+0.086	+0.437	<.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,449 associations by consensus.

Positive regulation of monoatomic ion transport by HFM1 expression — STOMACH

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