HEYL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HEYL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,024 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HEYL-associated proteins across cancer lineages are LUM, BGN, and SORBS3. Each is linked with HEYL in more than 9 cancer types. Because this analysis shows association rather than direction, both HEYL-to-partner and partner-to-HEYL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEYL versus LUM in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEYL→partner) and Y-score (partner→HEYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALUM →+0.852+0.891<.001<.001310
CCRCCBGN →+0.851+1.184<.001<.001310
UCECSORBS3 →+0.505+0.928<.001<.00139
OVLAMA4 →+0.622+1.041<.001<.00139
UCECLAMB1 →+0.596+1.174<.001<.00139
GBMNID2 →+0.718+0.808<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,024 associations by consensus.

HEYL vs LUM — BRCA

Per-sample scatter of HEYL vs LUM in BRCA (Pearson r = 0.56).

Explore this scatter interactively →

Exploration