HEY2

Across TCGA patient cohorts, HEY2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,420 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HEY2-associated proteins across cancer lineages are PCOLCE, CALD1, and CDH13. Each is linked with HEY2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HEY2-to-partner and partner-to-HEY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEY2 versus PCOLCE in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEY2→partner) and Y-score (partner→HEY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PCOLCE →	+0.810	+0.932	<.001	<.001	3	7
LSCC	CALD1 →	+0.704	+0.857	<.001	<.001	3	6
GBM	CDH13 →	+0.613	+0.742	.003	.002	3	6
PDAC	CNN3 →	+0.555	+0.479	<.001	<.001	3	6
LSCC	COL5A1 →	+0.627	+0.616	<.001	.004	3	6
COAD	FBLN2 →	+0.692	+0.507	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,420 associations by consensus.

HEY2 vs PCOLCE — HNSC

Explore this scatter interactively →