HEY2

Across TCGA cell cohorts, HEY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,916 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HEY2-associated GO terms across cancer lineages are Ventricular cardiac muscle cell development, Labyrinthine layer blood vessel development, and Labyrinthine layer development. Each is linked with HEY2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HEY2-to-partner and partner-to-HEY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ventricular cardiac muscle cell development grouped by HEY2-low versus HEY2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEY2→partner) and Y-score (partner→HEY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Ventricular cardiac muscle cell development →	-0.231	-1.551	.001	<.001	3	9
BLOOD_Lymphoma	Labyrinthine layer blood vessel development →	-0.234	-1.037	<.001	<.001	3	9
BONE	Labyrinthine layer development →	-0.247	-0.445	.001	.007	3	9
LUNG_NSCLC_LUAD	Regulation of potassium ion transmembrane transport →	-0.107	-0.562	<.001	<.001	3	9
BREAST	Regulation of nucleotide-excision repair →	+0.115	+1.680	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Regulation of potassium ion transport →	-0.109	-0.759	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

Ventricular cardiac muscle cell development by HEY2 expression — BREAST

Explore this box plot interactively →