Across TCGA patient cohorts, HEXIM1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,421 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEXIM1-associated genes across cancer lineages are P3H4, FXR1, and BRCA1. Each is linked with HEXIM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HEXIM1-to-partner and partner-to-HEXIM1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXIM1→partner) and Y-score (partner→HEXIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	P3H4 →	+0.820	+0.341	<.001	<.001	3	7
LSCC	FXR1 →	+0.520	+0.233	<.001	<.001	3	6
LSCC	BRCA1 →	+0.928	+0.429	<.001	<.001	3	6
UCEC	SASS6 →	+0.668	+0.307	.002	.002	3	6
BRCA	NKIRAS2 →	+0.419	+0.347	<.001	<.001	3	6
BRCA	DNAJC7 →	+0.405	+0.374	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,421 associations by consensus.

Exploration

HEXIM1 survival (RNA) · tumor vs normal (RNA) · all HEXIM1 data types