HEXIM1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HEXIM1 mutation is significantly associated with the RNA expression of many other genes, with 1,579 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HEXIM1-associated genes across cancer lineages are RNA5SP325, RNU6-1081P, and BPY2DP. Each is linked with HEXIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEXIM1-to-partner and partner-to-HEXIM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXIM1→partner) and Y-score (partner→HEXIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP325 →+0.169+4.837<.001.00332
HNSCRNU6-1081P →+0.241+5.468<.001.00232
COADBPY2DP →+0.234+5.824<.001.00132
COADTBC1D26-AS1 →+0.183+4.624<.001.00132
LIHCKRTAP5-3 →+0.040+4.878<.001.00532
LIHCC1DP4 →+0.127+4.567<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,579 associations by consensus.

Exploration