Across TCGA cell cohorts, HEXIM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,618 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HEXIM1-associated GO terms across cancer lineages are Negative regulation of transcription elongation by RNA polymerase II, Negative regulation of DNA-templated transcription, elongation, and Interleukin-23-mediated signaling pathway. Each is linked with HEXIM1 in more than 12 cancer types. Because this analysis shows association rather than direction, both HEXIM1-to-partner and partner-to-HEXIM1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXIM1→partner) and Y-score (partner→HEXIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of transcription elongation by RNA polymerase II →	+0.095	+1.088	<.001	<.001	3	13
URINARY_TRACT	Negative regulation of DNA-templated transcription, elongation →	+0.100	+0.677	.001	<.001	3	10
STOMACH	Interleukin-23-mediated signaling pathway →	+0.162	+0.699	.007	.006	3	8
UPPER_AERODIGESTIVE_TRACT	R-loop processing →	+0.100	+0.925	.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.088	+0.973	<.001	<.001	3	8
BLOOD_Lymphoma	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.044	+0.874	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,618 associations by consensus.

Exploration

HEXIM1 survival (RNA) · tumor vs normal (RNA) · all HEXIM1 data types