Across TCGA cell cohorts, HEXIM1 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HEXIM1-associated genes across cancer lineages are TMCO5A, CCDC179, and SLC32A1. Each is linked with HEXIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEXIM1-to-partner and partner-to-HEXIM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXIM1→partner) and Y-score (partner→HEXIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC179 →	+0.067	+4.095	<.001	.009	3	1
BLOOD_Leukemia	SLC32A1 →	+0.781	+3.223	<.001	.004	3	1
BLOOD_Leukemia	PHOX2B →	+0.022	+4.687	<.001	<.001	3	1
BLOOD_Leukemia	IL5 →	+0.213	+3.853	<.001	.002	3	1
BLOOD_Leukemia	MUC5B →	+0.393	+3.474	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Exploration

HEXIM1 survival (RNA) · tumor vs normal (RNA) · all HEXIM1 data types