HEXA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HEXA protein abundance is significantly associated with the protein abundance of many other proteins, with 22,364 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HEXA-associated proteins across cancer lineages are HEXB, CTSA, and GALNS. Each is linked with HEXA in more than 9 cancer types. Because this analysis shows association rather than direction, both HEXA-to-partner and partner-to-HEXA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HEXA→partner) and Y-score (partner→HEXA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADHEXB →+0.564+0.506<.001<.001310
GBMCTSA →+0.457+0.561<.001<.00139
LUADGALNS →+0.684+0.510<.001<.00139
BRCAASAH1 →+0.562+0.271<.001<.00139
LUADFUCA1 →+0.777+0.402<.001<.00139
COADGAA →+0.539+0.454<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,364 associations by consensus.

Exploration