HES7

Across TCGA cell cohorts, HES7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,007 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HES7-associated GO terms across cancer lineages are UTP biosynthetic process, Telomere maintenance via telomere lengthening, and IMP biosynthetic process. Each is linked with HES7 in more than 8 cancer types. Because this analysis shows association rather than direction, both HES7-to-partner and partner-to-HES7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTP biosynthetic process grouped by HES7-low versus HES7-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HES7→partner) and Y-score (partner→HES7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	UTP biosynthetic process →	+0.142	+1.238	.006	.008	3	9
BONE	Telomere maintenance via telomere lengthening →	+0.087	+0.734	.003	.003	3	8
URINARY_TRACT	IMP biosynthetic process →	+0.223	+1.853	<.001	.004	3	8
LARGE_INTESTINE	AMPA glutamate receptor clustering →	+0.734	+0.867	.003	.004	3	8
LARGE_INTESTINE	Glutamate receptor clustering →	+0.734	+0.867	.003	.004	3	8
LUNG_SCLC	GTP biosynthetic process →	+0.162	+1.027	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

UTP biosynthetic process by HES7 expression — LIVER

Explore this box plot interactively →