HES5

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HES5 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,725 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HES5-associated proteins across cancer lineages are FYB1, SAMSN1, and SAMSN1_S23. Each is linked with HES5 in more than 4 cancer types. Because this analysis shows association rather than direction, both HES5-to-partner and partner-to-HES5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HES5→partner) and Y-score (partner→HES5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMFYB1 →-0.650-1.621<.001<.00135
GBMSAMSN1 →-0.626-2.316<.001<.00134
LSCCSAMSN1_S23 →-0.575-0.482<.001<.00134
CCRCCSAMSN1_S347 →-0.798-0.918<.001<.00134
HNSCTACC2 →+0.475+1.368<.001<.00134
CCRCCGBP2 →-0.605-0.942<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,725 associations by consensus.

Exploration