HES1

Across TCGA patient cohorts, HES1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,872 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HES1-associated proteins across cancer lineages are HES1_S12, RCSD1, and WAS. Each is linked with HES1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HES1-to-partner and partner-to-HES1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HES1 versus HES1_S12 in LUAD, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HES1→partner) and Y-score (partner→HES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HES1_S12 →	+0.744	+1.113	<.001	<.001	3	7
LSCC	RCSD1 →	-0.515	-0.745	<.001	<.001	3	5
GBM	WAS →	-0.443	-0.571	.001	.002	3	5
LSCC	RASAL3_S72 →	-0.782	-0.739	<.001	<.001	3	5
GBM	BTK →	-0.409	-0.604	<.001	.002	3	4
CCRCC	CCDC88B_S1379 →	-0.796	-1.187	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,872 associations by consensus.

HES1 vs HES1_S12 — LUAD

Explore this scatter interactively →