HERPUD1

Across TCGA patient cohorts, HERPUD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,487 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HERPUD1-associated genes across cancer lineages are PIM2, IGLV6-57, and IGHG1. Each is linked with HERPUD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HERPUD1-to-partner and partner-to-HERPUD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HERPUD1 versus PIM2 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HERPUD1→partner) and Y-score (partner→HERPUD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PIM2 →	+1.306	+0.821	<.001	<.001	3	7
HNSC	IGLV6-57 →	+2.073	+0.493	.001	<.001	3	7
BRCA	IGHG1 →	+3.468	+0.593	<.001	<.001	3	7
BRCA	IGHV6-1 →	+2.956	+0.589	<.001	<.001	3	7
OV	IGHV3-15 →	+3.623	+0.681	.002	.006	3	7
OV	IGKV1-12 →	+3.410	+0.690	.002	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,487 associations by consensus.

HERPUD1 vs PIM2 — HNSC

Explore this scatter interactively →