HERC5

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HERC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,629 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HERC5-associated proteins across cancer lineages are CMPK2, PSMB6, and XAF1. Each is linked with HERC5 in more than 9 cancer types. Because this analysis shows association rather than direction, both HERC5-to-partner and partner-to-HERC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HERC5 versus CMPK2 in HNSC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HERC5→partner) and Y-score (partner→HERC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCMPK2 →+0.851+1.323<.001<.001310
COADPSMB6 →-0.422-0.977<.001<.00139
COADXAF1 →+0.770+0.862.004.00139
UCECIRF9 →+0.425+0.825<.001<.00139
LSCCISG15 →+0.992+1.036<.001<.00139
HNSCMX2 →+0.919+1.484<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,629 associations by consensus.

HERC5 vs CMPK2 — HNSC

Per-sample scatter of HERC5 vs CMPK2 in HNSC (Pearson r = 0.75).

Explore this scatter interactively →

Exploration