HERC3

Across TCGA patient cohorts, HERC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,489 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HERC3-associated proteins across cancer lineages are UTRN, NARS2, and NFKB1. Each is linked with HERC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both HERC3-to-partner and partner-to-HERC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HERC3 versus UTRN in LUAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HERC3→partner) and Y-score (partner→HERC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UTRN →	+0.278	+0.313	<.001	<.001	3	4
BRCA	NARS2 →	-0.438	-0.082	<.001	.004	3	4
OV	NFKB1 →	+0.301	+0.097	<.001	.007	3	4
BRCA	PDLIM7 →	+0.484	+0.146	<.001	.001	3	4
CCRCC	DTX3L_S532 →	-0.677	-0.417	<.001	.003	3	4
CCRCC	CAST_S311 →	+0.550	+0.356	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,489 associations by consensus.

HERC3 vs UTRN — LUAD

Explore this scatter interactively →