HERC2P1

Across TCGA patient cohorts, HERC2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,417 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HERC2P1-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Protein ufmylation. Each is linked with HERC2P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both HERC2P1-to-partner and partner-to-HERC2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by HERC2P1-low versus HERC2P1-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HERC2P1→partner) and Y-score (partner→HERC2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.045	+0.022	<.001	<.001	3	13
KIRP	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.049	+0.022	<.001	<.001	3	13
KIRP	Protein ufmylation →	+0.054	+0.024	<.001	<.001	3	12
STAD	Telomere organization →	+0.047	+0.013	<.001	.001	3	12
STAD	RNA modification →	+0.046	+0.024	<.001	<.001	3	12
STAD	Telomere maintenance →	+0.050	+0.023	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,417 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by HERC2P1 expression — KIRP

Explore this box plot interactively →