Across TCGA patient cohorts, HEPACAM2 mutation is significantly associated with the RNA expression of many other genes, with 3,357 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HEPACAM2-associated genes across cancer lineages are GTF2A2, SLC3A2, and PPIP5K1. Each is linked with HEPACAM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HEPACAM2-to-partner and partner-to-HEPACAM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPACAM2→partner) and Y-score (partner→HEPACAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GTF2A2 →	+0.493	+4.141	<.001	<.001	3	4
UCEC	SLC3A2 →	+0.536	+4.010	<.001	<.001	3	3
UCEC	PPIP5K1 →	+0.440	+2.091	<.001	<.001	3	3
UCEC	GPKOW →	+0.379	+2.818	.002	.001	3	3
UCEC	WDR76 →	+0.718	+2.080	<.001	<.001	3	3
UCEC	VRK3 →	+0.301	+2.432	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,357 associations by consensus.

Exploration

HEPACAM2 survival (RNA) · tumor vs normal (RNA) · all HEPACAM2 data types