Across TCGA patient cohorts, HEPACAM2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HEPACAM2-associated genes across cancer lineages are JNK_pT183_Y185, STAT3_pY705, and ASNS. Each is linked with HEPACAM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HEPACAM2-to-partner and partner-to-HEPACAM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPACAM2→partner) and Y-score (partner→HEPACAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.189	-2.502	.001	.001	3	3
SKCM	STAT3_pY705 →	-0.342	-2.415	.001	.003	3	3
SKCM	ASNS →	+0.478	+3.321	.005	.009	3	3
UCEC	A-Raf_pS299 →	-0.115	-2.115	.007	.017	3	2
UCEC	MEK1 →	+0.317	+2.222	.016	.010	3	2
UCEC	Rab11 →	-0.110	-1.874	.036	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

HEPACAM2 survival (RNA) · tumor vs normal (RNA) · all HEPACAM2 data types