Across TCGA cell cohorts, HEPACAM2 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HEPACAM2-associated genes across cancer lineages are OR10H5, USP17L11, and MYF5. Each is linked with HEPACAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HEPACAM2-to-partner and partner-to-HEPACAM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPACAM2→partner) and Y-score (partner→HEPACAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10H5 →	+0.060	+4.044	<.001	.009	3	2
LUNG_NSCLC_LUAD	USP17L11 →	+0.066	+3.734	<.001	.006	3	2
LUNG_SCLC	MYF5 →	+0.045	+4.643	<.001	.004	3	1
LUNG_SCLC	PRAMEF12 →	+0.145	+4.269	<.001	.005	3	1
LUNG_SCLC	SERPINA7 →	+0.057	+4.817	<.001	.001	3	1
LUNG_SCLC	SHOX →	+0.358	+4.817	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

HEPACAM2 survival (RNA) · tumor vs normal (RNA) · all HEPACAM2 data types