HEPACAM

Across TCGA cell cohorts, HEPACAM mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HEPACAM-associated genes across cancer lineages are ACSM6, GPHB5, and CDSN. Each is linked with HEPACAM in more than 1 cancer types. Because this analysis shows association rather than direction, both HEPACAM-to-partner and partner-to-HEPACAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM6 grouped by HEPACAM-low versus HEPACAM-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEPACAM→partner) and Y-score (partner→HEPACAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ACSM6 →	+0.019	+4.087	.009	.009	3	2
LUNG_NSCLC_LUAD	GPHB5 →	+0.070	+4.887	<.001	.009	3	1
BLOOD_Leukemia	CDSN →	+0.121	+4.295	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACSM6 by HEPACAM expression — BLOOD_Leukemia

Explore this box plot interactively →