HELZ2

Across TCGA patient cohorts, HELZ2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,883 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HELZ2-associated proteins across cancer lineages are OGFR, OGFR_S378, and CMPK2. Each is linked with HELZ2 in more than 8 cancer types. Because this analysis shows association rather than direction, both HELZ2-to-partner and partner-to-HELZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HELZ2 versus OGFR in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HELZ2→partner) and Y-score (partner→HELZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OGFR →	+0.364	+0.880	<.001	<.001	3	9
UCEC	OGFR_S378 →	+0.474	+1.039	<.001	<.001	3	9
HNSC	CMPK2 →	+0.628	+0.814	<.001	<.001	3	8
LSCC	DDX58 →	+0.702	+1.119	<.001	<.001	3	8
BRCA	EIF2AK2 →	+0.324	+0.994	<.001	<.001	3	8
HNSC	IFIH1 →	+0.593	+0.746	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,883 associations by consensus.

HELZ2 vs OGFR — BRCA

Explore this scatter interactively →